Oborská-Oplová M, et al. (2025) An avoidance segment resolves a lethal nuclear-mitochondrial targeting conflict during ribosome assembly. Nat Cell Biol 27(2):336-346 PMID:39890954
Bittner E, et al. (2024) Proteins that carry dual targeting signals can act as tethers between peroxisomes and partner organelles. PLoS Biol 22(2):e3002508 PMID:38377076
Bykov YS and Schuldiner M (2024) Analysis of mitochondrial biogenesis and protein localization by genetic screens and automated imaging. Methods Enzymol 706:97-123 PMID:39455236
Reinhard J, et al. (2024) MemPrep, a new technology for isolating organellar membranes provides fingerprints of lipid bilayer stress. EMBO J 43(8):1653-1685 PMID:38491296
Barbieri G, et al. (2023) Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation. J Biol Chem 299(3):102895 PMID:36639027
Cohen N, et al. (2023) A systematic proximity ligation approach to studying protein-substrate specificity identifies the substrate spectrum of the Ssh1 translocon. EMBO J 42(11):e113385 PMID:37073826
Ekal L, et al. (2023) Spindle Position Checkpoint Kinase Kin4 Regulates Organelle Transport in Saccharomyces cerevisiae. Biomolecules 13(7) PMID:37509134
Fenech EJ, et al. (2023) A toolbox for systematic discovery of stable and transient protein interactors in baker's yeast. Mol Syst Biol 19(2):e11084 PMID:36651308
Fischer S, et al. (2023) Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes. Biol Chem 404(2-3):135-155 PMID:36122347
Mark M, et al. (2023) Systematic Approaches to Study Eclipsed Targeting of Proteins Uncover a New Family of Mitochondrial Proteins. Cells 12(11) PMID:37296670
Yifrach E, et al. (2023) Determining the targeting specificity of the selective peroxisomal targeting factor Pex9. Biol Chem 404(2-3):121-133 PMID:36279206
Bisinski DD, et al. (2022) Cvm1 is a component of multiple vacuolar contact sites required for sphingolipid homeostasis. J Cell Biol 221(8) PMID:35766971
Cohen N, et al. (2022) A Similarity-Based Method for Predicting Enzymatic Functions in Yeast Uncovers a New AMP Hydrolase. J Mol Biol 434(7):167478 PMID:35123996
Yifrach E, et al. (2022) Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions. Mol Syst Biol 18(9):e11186 PMID:36164978
Backes S, et al. (2021) The chaperone-binding activity of the mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress. Cell Rep 35(1):108936 PMID:33826901
Eisenberg-Bord M, et al. (2021) Cnm1 mediates nucleus-mitochondria contact site formation in response to phospholipid levels. J Cell Biol 220(11) PMID:34694322
Laborenz J, et al. (2021) The ER protein Ema19 facilitates the degradation of nonimported mitochondrial precursor proteins. Mol Biol Cell 32(8):664-674 PMID:33596095
Lemus L, et al. (2021) Post-ER degradation of misfolded GPI-anchored proteins is linked with microautophagy. Curr Biol 31(18):4025-4037.e5 PMID:34314677
Colaco A, et al. (2020) Unbiased yeast screens identify cellular pathways affected in Niemann-Pick disease type C. Life Sci Alliance 3(7) PMID:32487688
Fenech EJ, et al. (2020) Double the Fun, Double the Trouble: Paralogs and Homologs Functioning in the Endoplasmic Reticulum. Annu Rev Biochem 89:637-666 PMID:32569522
Gabay-Maskit S, et al. (2020) A piggybacking mechanism enables peroxisomal localization of the glyoxylate cycle enzyme Mdh2 in yeast. J Cell Sci 133(24) PMID:33177075
Rosenthal M, et al. (2020) Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay. Proc Natl Acad Sci U S A 117(35):21432-21440 PMID:32817524
Saladi S, et al. (2020) The NADH Dehydrogenase Nde1 Executes Cell Death after Integrating Signals from Metabolism and Proteostasis on the Mitochondrial Surface. Mol Cell 77(1):189-202.e6 PMID:31668496
Schummer A, et al. (2020) Pex14p Phosphorylation Modulates Import of Citrate Synthase 2 Into Peroxisomes in Saccharomyces cerevisiae. Front Cell Dev Biol 8:549451 PMID:33042991
Wang Y, et al. (2020) Noncanonical regulation of phosphatidylserine metabolism by a Sec14-like protein and a lipid kinase. J Cell Biol 219(5) PMID:32303746
Wong S, et al. (2020) Cargo Release from Myosin V Requires the Convergence of Parallel Pathways that Phosphorylate and Ubiquitylate the Cargo Adaptor. Curr Biol 30(22):4399-4412.e7 PMID:32916113
Antunes D, et al. (2019) Overexpression of branched-chain amino acid aminotransferases rescues the growth defects of cells lacking the Barth syndrome-related gene TAZ1. J Mol Med (Berl) 97(2):269-279 PMID:30604168
Barbosa AD, et al. (2019) Compartmentalized Synthesis of Triacylglycerol at the Inner Nuclear Membrane Regulates Nuclear Organization. Dev Cell 50(6):755-766.e6 PMID:31422915
Bykov YS, et al. (2019) High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding. J Cell Biol 218(8):2797-2811 PMID:31289126
Castells-Ballester J, et al. (2019) Translational Regulation of Pmt1 and Pmt2 by Bfr1 Affects Unfolded Protein O-Mannosylation. Int J Mol Sci 20(24) PMID:31835530
Chao JT, et al. (2019) Transfer of the Septin Ring to Cytokinetic Remnants in ER Stress Directs Age-Sensitive Cell-Cycle Re-entry. Dev Cell 51(2):173-191.e5 PMID:31564614
Dubreuil B, et al. (2019) YeastRGB: comparing the abundance and localization of yeast proteins across cells and libraries. Nucleic Acids Res 47(D1):D1245-D1249 PMID:30357397
Haribowo AG, et al. (2019) Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiae. Mol Biol Cell 30(22):2814-2826 PMID:31509475
Li J, et al. (2019) AMPK regulates ESCRT-dependent microautophagy of proteasomes concomitant with proteasome storage granule assembly during glucose starvation. PLoS Genet 15(11):e1008387 PMID:31738769
Odendall F, et al. (2019) The mitochondrial intermembrane space-facing proteins Mcp2 and Tgl2 are involved in yeast lipid metabolism. Mol Biol Cell 30(21):2681-2694 PMID:31483742
Weill U, et al. (2019) Protein Topology Prediction Algorithms Systematically Investigated in the Yeast Saccharomyces cerevisiae. Bioessays 41(8):e1800252 PMID:31297843
Chuartzman SG and Schuldiner M (2018) Database for High Throughput Screening Hits (dHITS): a simple tool to retrieve gene specific phenotypes from systematic screens done in yeast. Yeast 35(7):477-483 PMID:29574976
Eisenberg-Bord M, et al. (2018) Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation. J Cell Biol 217(1):269-282 PMID:29187527
Gabay-Maskit S, et al. (2018) Validation of a yeast malate dehydrogenase 2 (Mdh2) antibody tested for use in western blots. F1000Res 7:130 PMID:29568493
Hansen KG, et al. (2018) An ER surface retrieval pathway safeguards the import of mitochondrial membrane proteins in yeast. Science 361(6407):1118-1122 PMID:30213914
Shai N, et al. (2018) Systematic mapping of contact sites reveals tethers and a function for the peroxisome-mitochondria contact. Nat Commun 9(1):1761 PMID:29720625
Vitali DG, et al. (2018) The GET pathway can increase the risk of mitochondrial outer membrane proteins to be mistargeted to the ER. J Cell Sci 131(10) PMID:29661846
Weill U, et al. (2018) Toolbox: Creating a systematic database of secretory pathway proteins uncovers new cargo for COPI. Traffic 19(5):370-379 PMID:29527758
Apel AR, et al. (2017) Syp1 regulates the clathrin-mediated and clathrin-independent endocytosis of multiple cargo proteins through a novel sorting motif. Mol Biol Cell 28(18):2434-2448 PMID:28701344
Cohen N, et al. (2017) Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling. J Cell Sci 130(19):3222-3233 PMID:28794014
Eapen VV, et al. (2017) A pathway of targeted autophagy is induced by DNA damage in budding yeast. Proc Natl Acad Sci U S A 114(7):E1158-E1167 PMID:28154131
Haßdenteufel S, et al. (2017) hSnd2 protein represents an alternative targeting factor to the endoplasmic reticulum in human cells. FEBS Lett 591(20):3211-3224 PMID:28862756
Kruzel-Davila E, et al. (2017) APOL1-Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes. J Am Soc Nephrol 28(4):1117-1130 PMID:27864431
Lebesgue N, et al. (2017) Combining Deep Sequencing, Proteomics, Phosphoproteomics, and Functional Screens To Discover Novel Regulators of Sphingolipid Homeostasis. J Proteome Res 16(2):571-582 PMID:28152593
Zatorska E, et al. (2017) Cellular Consequences of Diminished Protein O-Mannosyltransferase Activity in Baker's Yeast. Int J Mol Sci 18(6) PMID:28598353
Aviram N, et al. (2016) The SND proteins constitute an alternative targeting route to the endoplasmic reticulum. Nature 540(7631):134-138 PMID:27905431
Li J, et al. (2016) An unrecognized function for COPII components in recruiting the viral replication protein BMV 1a to the perinuclear ER. J Cell Sci 129(19):3597-3608 PMID:27539921
Yifrach E, et al. (2016) Characterization of proteome dynamics during growth in oleate reveals a new peroxisome-targeting receptor. J Cell Sci 129(21):4067-4075 PMID:27663510
Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
Dobzinski N, et al. (2015) Starvation-Dependent Regulation of Golgi Quality Control Links the TOR Signaling and Vacuolar Protein Sorting Pathways. Cell Rep 12(11):1876-86 PMID:26344761
Sauerwald J, et al. (2015) Genome-Wide Screens in Saccharomyces cerevisiae Highlight a Role for Cardiolipin in Biogenesis of Mitochondrial Outer Membrane Multispan Proteins. Mol Cell Biol 35(18):3200-11 PMID:26149385
Breker M, et al. (2014) LoQAtE--Localization and Quantitation ATlas of the yeast proteomE. A new tool for multiparametric dissection of single-protein behavior in response to biological perturbations in yeast. Nucleic Acids Res 42(Database issue):D726-30 PMID:24150937
Elbaz-Alon Y, et al. (2014) The yeast oligopeptide transporter Opt2 is localized to peroxisomes and affects glutathione redox homeostasis. FEMS Yeast Res 14(7):1055-67 PMID:25130273
Lesnik C, et al. (2014) OM14 is a mitochondrial receptor for cytosolic ribosomes that supports co-translational import into mitochondria. Nat Commun 5:5711 PMID:25487825
Vieira NM, et al. (2014) A defect in the RNA-processing protein HNRPDL causes limb-girdle muscular dystrophy 1G (LGMD1G). Hum Mol Genet 23(15):4103-10 PMID:24647604
Yofe I and Schuldiner M (2014) Primers-4-Yeast: a comprehensive web tool for planning primers for Saccharomyces cerevisiae. Yeast 31(2):77-80 PMID:24408512
Yofe I, et al. (2014) Accurate, model-based tuning of synthetic gene expression using introns in S. cerevisiae. PLoS Genet 10(6):e1004407 PMID:24968317
Cohen Y, et al. (2013) The yeast p5 type ATPase, spf1, regulates manganese transport into the endoplasmic reticulum. PLoS One 8(12):e85519 PMID:24392018
Hecht KA, et al. (2013) Characterization of an M28 metalloprotease family member residing in the yeast vacuole. FEMS Yeast Res 13(5):471-84 PMID:23679341
Papić D, et al. (2013) The role of Djp1 in import of the mitochondrial protein Mim1 demonstrates specificity between a cochaperone and its substrate protein. Mol Cell Biol 33(20):4083-94 PMID:23959800
Peters LZ, et al. (2013) Formation and dissociation of proteasome storage granules are regulated by cytosolic pH. J Cell Biol 201(5):663-71 PMID:23690178
Powis K, et al. (2013) Get3 is a holdase chaperone and moves to deposition sites for aggregated proteins when membrane targeting is blocked. J Cell Sci 126(Pt 2):473-83 PMID:23203805
Schuldiner M and Weissman JS (2013) The contribution of systematic approaches to characterizing the proteins and functions of the endoplasmic reticulum. Cold Spring Harb Perspect Biol 5(3):a013284 PMID:23359093
Herzig Y, et al. (2012) A systematic approach to pair secretory cargo receptors with their cargo suggests a mechanism for cargo selection by Erv14. PLoS Biol 10(5):e1001329 PMID:22629230
Nadler-Holly M, et al. (2012) Interactions of subunit CCT3 in the yeast chaperonin CCT/TRiC with Q/N-rich proteins revealed by high-throughput microscopy analysis. Proc Natl Acad Sci U S A 109(46):18833-8 PMID:23112166
Spokoini R, et al. (2012) Confinement to organelle-associated inclusion structures mediates asymmetric inheritance of aggregated protein in budding yeast. Cell Rep 2(4):738-47 PMID:23022486
Cohen Y and Schuldiner M (2011) Advanced methods for high-throughput microscopy screening of genetically modified yeast libraries. Methods Mol Biol 781:127-59 PMID:21877281
Hoppins S, et al. (2011) A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria J Cell Biol
Breker M and Schuldiner M (2009) Explorations in topology-delving underneath the surface of genetic interaction maps. Mol Biosyst 5(12):1473-81 PMID:19763324
Jonikas MC, et al. (2009) Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323(5922):1693-7 PMID:19325107
Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10 PMID:17314980
Haass FA, et al. (2007) Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proc Natl Acad Sci U S A 104(46):18079-84 PMID:17989219
Schuldiner M, et al. (2006) Quantitative genetic analysis in Saccharomyces cerevisiae using epistatic miniarray profiles (E-MAPs) and its application to chromatin functions. Methods 40(4):344-52 PMID:17101447
Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19 PMID:16269340