Click on a phenotype to go to its specific page within SGD; drag any of the phentoype objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram.
Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| HSV2 | micronucleophagy: abnormal | classical genetics | null Allele: hsv2-Δ | S288C | Details: decreased rate of micronucleophagy (piecemeal microautophagy of the nucleus) | Krick R, et al. (2008) PMID:18769150 | |
| SCS2 | micronucleophagy: decreased | classical genetics | null Allele: scs2-Δ | S288C | 200 ng/ml sirolimus | Details: impaired micronucleophagic degradation of nucleolar proteins, such as Nop1-GFP, by micronucleophagy after TORC1 inactivation in rapamycin-treated cells | Manik MIN, et al. (2024) PMID:39232457 |
| SCS22 | micronucleophagy: decreased | classical genetics | null Allele: scs22-Δ | S288C | 200 ng/ml sirolimus | Details: impaired micronucleophagic degradation of nucleolar proteins, such as Nop1-GFP, by micronucleophagy after TORC1 inactivation in rapamycin-treated cells | Manik MIN, et al. (2024) PMID:39232457 |
| SND3 | micronucleophagy: absent | classical genetics | null Allele: snd3-Δ | S288C | Media: nitrogen-starvation Details: piecemeal microautophagy of the nucleus (PMN) is completely absent in the nitrogen-starved null mutant | Tosal-Castano S, et al. (2021) PMID:33472077 | |
| VPS24 | micronucleophagy: absent Reporter: Nop1-GFP | classical genetics | null Allele: vps24-Δ | S288C | 200 ng/ml sirolimus | Details: abolition of free GFP production using a Nop1-GFP processing assay, demonstrating the requirement for ESCRT-III in the nucleophagic degradation of nucleolar proteins after TORC1 inactivation with rapamycin; also required for associated rDNA condensation | Tasnin MN, et al. (2025) PMID:39642706 |
| VPS27 | micronucleophagy: absent Reporter: Nop1-GFP | classical genetics | null Allele: vps27-Δ | S288C | 200 ng/ml sirolimus | Details: abolition of free GFP production using a Nop1-GFP processing assay, demonstrating the requirement for ESCRT-0 in the nucleophagic degradation of nucleolar proteins after TORC1 inactivation with rapamycin; also required for associated rDNA condensation and nucleolar remodeling | Tasnin MN, et al. (2025) PMID:39642706 |
| VPS28 | micronucleophagy: absent Reporter: Nop1-GFP | classical genetics | null Allele: vps28-Δ | S288C | 200 ng/ml sirolimus | Details: abolition of free GFP production using a Nop1-GFP processing assay, demonstrating the requirement for ESCRT-I in the nucleophagic degradation of nucleolar proteins after TORC1 inactivation with rapamycin | Tasnin MN, et al. (2025) PMID:39642706 |
| VPS36 | micronucleophagy: absent Reporter: Nop1-GFP | classical genetics | null Allele: vps36-Δ | S288C | 200 ng/ml sirolimus | Details: abolition of free GFP production using a Nop1-GFP processing assay, demonstrating the requirement for ESCRT-II in the nucleophagic degradation of nucleolar proteins after TORC1 inactivation with rapamycin | Tasnin MN, et al. (2025) PMID:39642706 |
| VPS4 | micronucleophagy: absent Reporter: Nop1-GFP | classical genetics | null Allele: vps4-Δ | S288C | 200 ng/ml sirolimus | Details: abolition of free GFP production using a Nop1-GFP processing assay, demonstrating that ESCRT is required for the nucleophagic degradation of nucleolar proteins after TORC1 inactivation with rapamycin | Tasnin MN, et al. (2025) PMID:39642706 |