Reference: Horikoshi M, et al. (1989) Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box. Nature 341(6240):299-303

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Abstract


The TATA sequence-binding factor TFIID plays a central role both in promoter activation by RNA polymerase II and other common initiation factors, and in promoter regulation by gene-specific factors. The sequence of yeast TFIID, which seems to be encoded by a single gene, contains interesting structural motifs that are possibly involved in these functions, and is similar to sequences of bacterial sigma factors.

Reference Type
Comparative Study | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.
Authors
Horikoshi M, Wang CK, Fujii H, Cromlish JA, Weil PA, Roeder RG
Primary Lit For
SPT15 | General transcription factor complex TFIID | DNA-directed RNA polymerase II complex

Gene Ontology Annotations 1 entry for 1 gene


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Gene/ComplexQualifierGene Ontology TermAnnotation ExtensionEvidenceSourceAssigned On
SPT15enablesRNA polymerase II core promoter sequence-specific DNA bindingIDASGD2013-08-07
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