Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
10 entries for 7 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| HNT1 | competitive fitness: decreased | competitive growth fitness profiling using complete deletion alleles | null Allele: hnt1-Δ | S288C | Media: minimal medium Details: Relative fitness score: 0.95 | Breslow DK, et al. (2008) PMID:18622397 | |
| HNT1 | competitive fitness: decreased | systematic mutation set | null Allele: hnt1-Δ | S288C | Media: synthetic oak exudate medium, OAK | Qian W, et al. (2012) PMID:23103169 | |
| HNT1 | desiccation resistance: decreased | homozygous diploid, systematic mutation set | null Allele: hnt1-Δ | S288C | Details: mutant displays greatly reduced growth in rich medium after exposure to air-drying stress for one day | Shima J, et al. (2008) PMID:18224659 | |
| HNT1 | oxidative stress resistance: increased | competitive growth | null Allele: hnt1-Δ | S288C | 1 mM paraquat | Helsen J, et al. (2020) PMID:32658971 | |
| HNT1 | resistance to chemicals: decreased | systematic mutation set | null Allele: hnt1-Δ | S288C | 45 ng/ml cycloheximide | Alamgir M, et al. (2010) PMID:20691087 | |
| HNT1 | resistance to chemicals: decreased | systematic mutation set | null Allele: hnt1-Δ | S288C | 40 mg/ml streptomycin | Alamgir M, et al. (2010) PMID:20691087 | |
| HNT1 | resistance to chemicals: decreased | homozygous diploid, systematic mutation set | null Allele: hnt1-Δ | S288C | 0.78 mM diethyl phthalate | Details: DEP sensitive mutants are defined as those with a logarithm of fitness coefficient (logFC) < − 0.5 based on a homozygous profiling (HOP) assay | Goh CJH, et al. (2022) PMID:35715465 |
| HNT1 | stress resistance: decreased | homozygous diploid, competitive growth | null Allele: hnt1-Δ | S288C | 1 uM zinc dichloride | Media: zinc deficiency | North M, et al. (2012) PMID:22685415 |
| HNT1 | utilization of nitrogen source: decreased rate | systematic mutation set prototrophic version of yeast deletion collection | null Allele: hnt1-Δ | S288C | allantoin | VanderSluis B, et al. (2014) PMID:24721214 | |
| HNT1 | viable | systematic mutation set | null Allele: hnt1-Δ | S288C | Giaever G, et al. (2002) PMID:12140549 |
An interaction is defined as an experimentally observed physical or genetic interaction between two genes. There may be more than one row listed for the same interactor if the interaction between it and the given gene was observed in separate studies. All interactions listed in SGD are curated by BioGRID.
Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details about experiment type and any other genes involved in the interaction.
| Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Allele | Assay | Annotation | Action | Phenotype | SGA score | P-value | Source | Reference | Note |
|---|
This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
Addgene Plasmids | DNASU Plasmids | PlasmID | Thermo Scientific | YGRC
dHITS | FitDB | HIPHOP Chemogenomics | HIP HOP Profiles | MetaboGeneCard | PROPHECY | SCMD | ScreenTroll | TheCellVision | Yeast Phenome
BioGRID | CYC2008 | DIP | GeneMANIA | IMP | InterologFinder | ModelArchive | TheCellMap | YeastRC Two-Hybrid