Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
3 entries for 3 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| YCL001W-B | metal resistance: increased | systematic mutation set | null Allele: ycl001w-b-Δ | S288C | lithium(1+) | Treatment: lithium chloride, 100 mM Details: null mutants exhibiting growth between 110-150% growth at 100 mM LiCl were classified as having a medium level of resistance; screen consisted of a 4 step approach including qualitative assessment on Li-agar plates, liquid microplate assessment, tertiary screening in liquid and a quaternary screen using Li2SO4, followed by classification based on the degree of sensitivity | Fierling N, et al. (2024) PMID:38142127 |
| YCL001W-B | resistance to chemicals: decreased | systematic mutation set | null Allele: ycl001w-b-Δ | S288C | 0.2 mM 2,4-dinitrophenol | Details: increased sensitivity to the IC25 concentration of 2,4-DNP relative to wt | Johnston NR, et al. (2020) PMID:32670247 |
| YCL001W-B | viable | systematic mutation set | null Allele: ycl001w-b-Δ | S288C | Kastenmayer JP, et al. (2006) PMID:16510898 |
An interaction is defined as an experimentally observed physical or genetic interaction between two genes. There may be more than one row listed for the same interactor if the interaction between it and the given gene was observed in separate studies. All interactions listed in SGD are curated by BioGRID.
Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details about experiment type and any other genes involved in the interaction.
| Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Allele | Assay | Annotation | Action | Phenotype | SGA score | P-value | Source | Reference | Note |
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This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
Addgene Plasmids | DNASU Plasmids | PlasmID | Thermo Scientific | YGRC
dHITS | FitDB | HIPHOP Chemogenomics | HIP HOP Profiles | MetaboGeneCard | PROPHECY | SCMD | ScreenTroll | TheCellVision | Yeast Phenome
BioGRID | CYC2008 | GeneMANIA | IMP | InterologFinder | ModelArchive | TheCellMap