Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
7 entries for 7 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| MCM1 | bud morphology: abnormal | classical genetics | conditional Allele: mcm1-110L C-terminal truncation; insertional frameshift after AA 110 | Other | Temperature: semi-permissive temperature, 30 °C Details: multiple, elongated, nucleated buds | Elble R and Tye BK (1992) PMID:1421579 | |
| MCM1 | cell cycle progression in M phase: arrested | classical genetics | conditional Allele: mcm1-110L C-terminal truncation; insertional frameshift after AA 110 | Other | Temperature: elevated temperature, 37 °C Details: 89% arrest with large, elongated buds, a single, undivided nucleus in or near the neck, and close to 2n DNA after 4 hours | Elble R and Tye BK (1992) PMID:1421579 | |
| MCM1 | chromosome/plasmid maintenance: abnormal | classical genetics | conditional Allele: mcm1-110L C-terminal truncation; insertional frameshift after AA 110 | Other | Temperature: semi-permissive temperature, 30 °C Details: ARS-specific minichromosome maintenance defect; 50% loss/generation for ARS1, compared to 10% for ARS120-containing plasmids | Elble R and Tye BK (1992) PMID:1421579 | |
| MCM1 | heat sensitivity: increased | classical genetics | conditional Allele: mcm1-110L C-terminal truncation; insertional frameshift after AA 110 | Other | Temperature: elevated temperature, 37 °C | Elble R and Tye BK (1991) PMID:1961765 | |
| MCM1 | mating response: abnormal | classical genetics | conditional Allele: mcm1-110L C-terminal truncation; insertional frameshift after AA 110 | Other | Temperature: semi-permissive temperature, 30 °C Details: severe mating defect in alpha cells; fail to mate with a cells but mate well with alpha cells | Elble R and Tye BK (1991) PMID:1961765 | |
| MCM1 | nuclear morphology: abnormal | classical genetics | conditional Allele: mcm1-110L C-terminal truncation; insertional frameshift after AA 110 | Other | Temperature: semi-permissive temperature, 30 °C Details: irregular stretched-out nuclear shapes, usually located near the bud neck; often appear connected to nuclei in adjacent buds | Elble R and Tye BK (1992) PMID:1421579 | |
| MCM1 | vegetative growth: decreased rate | classical genetics | conditional Allele: mcm1-110L C-terminal truncation; insertional frameshift after AA 110 | Other | Temperature: semi-permissive temperature, 30 °C | Elble R and Tye BK (1991) PMID:1961765 |
This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
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