Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
4 entries for 1 phenotypeIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| DUN1 | protein/peptide distribution: abnormal Reporter: Rnr2p | classical genetics | null Allele: dun1-D328A D328A; kinase domain mutation | S288C | 100 uM disodium 4,7-diphenyl-1,10-phenanthroline 4',4''-disulfonate | Details: Dun1p kinase activity is required for the nuclear-to-cytoplasmic redistribution of Rnr2p in response to iron limitation | Sanvisens N, et al. (2016) PMID:26970775 |
| DUN1 | protein/peptide distribution: abnormal Reporter: Rnr2p | classical genetics | null Allele: dun1-D328A D328A; kinase domain mutation | S288C | 0.04% methyl methanesulfonate | Details: Dun1p kinase activity is required for the nuclear-to-cytoplasmic redistribution of Rnr2p in response to MMS-induced genotoxic stress | Sanvisens N, et al. (2016) PMID:26970775 |
| DUN1 | protein/peptide distribution: abnormal Reporter: Rnr4p | classical genetics | null Allele: dun1-D328A D328A; kinase domain mutation | S288C | 100 uM disodium 4,7-diphenyl-1,10-phenanthroline 4',4''-disulfonate | Details: Dun1p kinase activity is required for the nuclear-to-cytoplasmic redistribution of Rnr4p in response to iron limitation | Sanvisens N, et al. (2016) PMID:26970775 |
| DUN1 | protein/peptide distribution: abnormal Reporter: Rnr4p | classical genetics | null Allele: dun1-D328A D328A; kinase domain mutation | S288C | 0.04% methyl methanesulfonate | Details: Dun1p kinase activity is required for the nuclear-to-cytoplasmic redistribution of Rnr4p in response to MMS-induced genotoxic stress | Sanvisens N, et al. (2016) PMID:26970775 |
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