Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
6 entries for 3 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| TEL2 | chromosome/plasmid maintenance: decreased | heterozygous diploid | null Allele: tel2-Δ | Other | Details: increased rate of loss of chromosome III per cell division | Runge KW and Zakian VA (1996) PMID:8649421 | |
| TEL2 | inviable | systematic mutation set | null Allele: tel2-Δ | S288C | Giaever G, et al. (2002) PMID:12140549 | ||
| TEL2 | inviable | classical genetics | null Allele: tel2-Δ | Other | Details: spores germinate and give rise to microcolonies of 2-8 cells; cells are large and contain blebs or knobs | Runge KW and Zakian VA (1996) PMID:8649421 | |
| TEL2 | resistance to chemicals: decreased | heterozygous diploid, systematic mutation set | null Allele: tel2-Δ | S288C | 20 μg/mL actinomycin D | Lum PY, et al. (2004) PMID:14718172 | |
| TEL2 | resistance to chemicals: decreased | heterozygous diploid, systematic mutation set | null Allele: tel2-Δ | S288C | 200 μg/mL sulfamethoxazole | Lum PY, et al. (2004) PMID:14718172 | |
| TEL2 | resistance to chemicals: decreased | systematic mutation set | null Allele: tel2-Δ | S288C | 4 ng/ml sirolimus | Details: sirolimus is rapamycin | Nicastro R, et al. (2021) PMID:33690632 |
This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
Addgene Plasmids | DNASU Plasmids | PlasmID | Thermo Scientific | YGRC
dHITS | FitDB | HIPHOP Chemogenomics | HIP HOP Profiles | PhenoM | PROPHECY | SCMD | ScreenTroll | TheCellVision | Yeast Phenome
BioGRID | CYC2008 | DIP | GeneMANIA | IMP | InterologFinder | ModelArchive | TheCellMap